Overweight/obese adults with symptomatic COVID-19 treated with metformin are less likely to develop long COVID (COVID-OUT)

Clinical Question

Is metformin effective in preventing long COVID in overweight or obese adults with symptomatic COVID-19 infections?

Bottom line

Among overweight or obese adults with acute symptomatic COVID-19, treatment with metformin modestly reduced the frequency of developing self-reported long COVID 6 months after infection. 1b-

Study design: Randomized controlled trial (double-blinded)

Funding: Other

Setting: Outpatient (any)

Reviewer

Henry C. Barry, MD, MS
Professor
Michigan State University
East Lansing, MI


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Comments

Anonymous

Metformin in obese patients with Covid

Interesting that metformin reduces incidence of long Covid.

ARUP KUMAR DHARA

Impact assessment

Excellent

Anonymous

OVERWEIGT WITH METFORMINAND COVID19

GOOD TO KNOW