Fezolinetant: promising treatment for menopausal vasomotor symptoms (SKYLIGHT 1)

Clinical Question

Is fezolinetant effective for treating menopausal vasomotor symptoms?

Bottom line

Fezolinetant is a nonhormonal treatment that shows promise for effectively reducing menopausal vasomotor symptoms. Further research, including larger and longer studies, will be needed to verify its safety and effectiveness. 1b

Study design: Randomized controlled trial (double-blinded)

Funding: Industry

Setting: Outpatient (any)


Linda Speer, MD
Professor and Chair, Department of Family Medicine
University of Toledo
Toledo, OH

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new drug fezolinetant

decreases vasomotor sx in menopause