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Question clinique
What are the observed expulsion rates of intrauterine devices placed postpartum?
L’Essentiel
Intrauterine device (IUD) expulsion rates after postpartum placement vary markedly based on timing of placement, type of IUD, and mode of delivery. Higher rates of expulsion were observed for immediate and early inpatient placement (within 72 hours) than early outpatient placement (4 days to 4 weeks). Higher rates were observed with a levonorgestrel-releasing IUD (LNG-IUD) compared with a copper T-shaped IUD, and after vaginal delivery compared with cesarean delivery. These rates, as detailed in the synopsis, can help guide decision-making for individual patients. The highest complete expulsion rates (27% to 37%) were for the placement of a LNG-IUD within the first 3 days after vaginal delivery. This is clearly too high for routine use. Early outpatient placement of IUDs may be the best balance of lower expulsion rates and minimization of risk for a new pregnancy. 2a
Référence
Plan de l'etude: Meta-analysis (other)
Financement: Government
Cadre: Various (meta-analysis)
Sommaire
This meta-analysis of data from 48 studies with 7661 participants synthesized the literature to obtain pooled absolute rates of expulsion after postpartum placement of IUDs. Studies ranges in size from 7 to 2733 women, with follow-up ranging from 4 weeks to 5 years. The authors evaluated 3 postpartum time frames of less than 4 weeks—immediate placement (within 10 minutes), early inpatient (from 10 minutes to less than 72 hours), and early outpatient (from 72 hours to less than 4 weeks)—and the usual postpartum time frame of placement at 4 weeks or more. Studies that did not permit data analysis by these time frames were excluded. The authors limited the data to the 2 brands available in the United States: Mirena (LNG-IUD) and Paragard (copper T). They also separately considered vaginal and cesarean deliveries. For IUDs placed in the immediate time frame, the weighted mean average for complete expulsion rates were 27% for LNG-IUD after vaginal delivery (range 19% - 45%) and 12% for copper T after vaginal delivery (range 5% - 38%). The rates were lower after cesarean deliveries with little difference between device types: 2% (range 0 - 2%), and 4% (range 0 - 15%) for LNG-IUD and copper T, respectively. For IUD placements in the early inpatient period, the weighted mean average of complete expulsions rates were 37% for LNG-IUD after vaginal delivery (range 27% - 47%) and for 7% for copper T after vaginal delivery (range 4% - 24%). In 3 studies with 136 women, no expulsions occurred among women who had IUD placements in the early outpatient time frame.
Reviewer
Linda Speer, MD
Professor and Chair, Department of Family Medicine
University of Toledo
Toledo, OH
Commentaires
IUD placement
Early IUD placement is too messy.