Oral contraceptives and anti-androgens most effective for hirsutism pharmacotherapy

Question clinique

What are the most effective drug therapies for hirsutism?

L’Essentiel

Combination oral contraceptive pills (OCPs) are an excellent treatment option for women desiring medical therapy for hirsutism. Based on this meta-analysis, an accompanying practice guideline recommends adding an anti-androgen, such as finasteride, if there is an inadequate response within 6 months. The guideline also recommends avoiding monotherapy with an anti-androgen and avoiding the use of insulin sensitizers such as metformin because of the inconsistency of the evidence (J Clin Endocrinol Metab 2018;103:1233-57). 1a-

Plan de l'etude: Meta-analysis (randomized controlled trials)

Financement: Foundation

Cadre: Various (meta-analysis)

Reviewer

Mark H. Ebell, MD, MS
Professor
University of Georgia
Athens, GA


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Commentaires

Anonymous

good poem

Anonymous

if I need this info

Anonymous

This study is poorly designed. Therefore, not very useful for clinical application.

Anonymous

I have been using OCP's but not in conjuction with Finasteride. Usually have added Metformin next. Good info to know and I will certainly change what I am doing!