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Clinical Question
Is documented sudden hearing loss associated with COVID-19 infection or vaccines against it?
Bottom line
As compared with incidence rates before the onset of the COVID-19 pandemic, hearing loss rates did not increase in Finland, and neither COVID-19 infection nor vaccination was associated with an increase in the overall incidence of documented hearing loss. 1b
Reference
Study design: Cohort (retrospective)
Funding: Unknown/not stated
Setting: Population-based
Synopsis
This study was conducted in Finland, which has a health registry for all 5.5 million residents. They excluded people with a previous diagnosis of sensorineural hearing loss. Then, they evaluated the rate of diagnoses for hearing loss after the start of the vaccination rollout. Overall rates of hearing loss dipped a little at the start of the COVID-19 pandemic, but then returned to the baseline (pre–COVID-19) rate when measured month-to-month. Most of the population received a messenger RNA vaccine, and almost all of these were the Pfizer-BioNTech (BNT162b2) vaccine. Among people who received a COVID-19 vaccine, there was no uptick in diagnoses of hearing loss. In addition, there was no difference in rates of hearing loss with patients with a COVID-19 infection. A limitation of this study is that the authors used diagnoses of hearing loss rendered by specialists; there may be people with hearing loss who did not seek specialty care. Another study, conducted in Israel, found a small increase in hearing loss associated with this vaccine, but they also included the use of prednisone as a marker, which may have overidentified patients thought to have hearing loss.
Reviewer
Allen F. Shaughnessy, PharmD, MMedEd
Professor of Family Medicine
Tufts University
Boston, MA
Comments
Impact assessment
Very good
not often seen
hearing loss often neuro