Limited data: levetiracetam, ketogenic diet, and modified Atkins diet decrease seizure frequency in children younger than 3 years with epilepsy

Clinical Question

What are effective therapies for decreasing seizure frequency in children aged 1 month to 36 months with epilepsy?

Bottom line

The existing data on managing young children with epilepsy is sparse (only 6 randomized trials) and of low quality. The best available data suggest that levetiracetam, ketogenic diets, and the modified Atkins diet decrease seizure frequency. 2a-

Study design: Systematic review

Funding: Government

Setting: Various (meta-analysis)

Reviewer

Henry C. Barry, MD, MS
Professor
Michigan State University
East Lansing, MI


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Comments

ARUP KUMAR DHARA

Impact assessment

Excellent

Anonymous

Siezures in kids

Not my field but interesting

Anonymous

Very innovative

Very innovative