Adipose-derived stem cell injections provide borderline meaningful pain relief in adults with knee degenerative joint disease

Clinical Question

Are adipose-derived stem cell injections effective in adults with moderate degenerative joint disease of the knee?

Bottom line

In this study, after 6 months, adults with moderate degenerative joint disease of the knee who received stem cell injections were more likely to experience clinically meaningful improvements in pain and function than those who received saline injections. 1b-

Study design: Randomized controlled trial (double-blinded)

Funding: Industry

Setting: Outpatient (specialty)

Reviewer

Henry C. Barry, MD, MS
Professor
Michigan State University
East Lansing, MI


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Comments

Arup Kumar Dhara

Impact assessment

Excellent

Dhananjay Desai

A third comparator arm would have been nice

It would have been nice to have a corticosteroid comparator arm too, to see how ADSCs performed against steroid.

Anonymous

ADIPOSE STEMCELL

GOOD TO KNOW