Mindfulness-based stress reduction is noninferior to escitalopram for adults with anxiety disorder

Clinical Question

Is mindfulness-based stress reduction noninferior to escitalopram for the treatment of adults with anxiety disorders?

Bottom line

This study found that standard MBSR is noninferior to pharmacotherapy with escitalopram for the treatment of adults with anxiety disorders. The primary outcome measurement occurred at 8 weeks from baseline. At 6 months, the anxiety scores remained improved, despite only 52% and 28% of the escitalopram and MBSR groups, respectively, continuing their treatments. 1b

Study design: Randomized controlled trial (single-blinded)

Funding: Government

Setting: Outpatient (any)


David C. Slawson, MD
Professor and Vice Chair of Family Medicine for Education and Scholarship
Atrium Health
Professor of Family Medicine, UNC Chapel Hill
Charlotte, NC

Discuss this POEM



Impact assessment

Very good

Bertus Johannes Reitsma


so far best clinical results for anxiety is low dose CBD


Mindfullness as effe tive as meds

Clearly quality time with a qualified therapist is pivotal in dealing with anxiety disorders. Meds are a "band aid" to get patients through a rough time, but therapy will help them recover and learn coping skills.