More melatonin and CBD in melatonin gummies than indicated by the product label

Clinical Question

What is the actual quantity of melatonin and cannabidiol in over-the-counter melatonin gummies compared with the quantities declared on the labels?

Bottom line

Nearly 90% of melatonin gummy products analyzed in this study were inadequately labeled. The actual quantity of melatonin ranged from 74% to 347% of the labeled quantity. Similarly, the quantity of CBD ranged from 104% to 118% of the labeled quantity. Be sure to warn parents of the risk of excessive melatonin and CBD ingestion with the gummies. 2b

Study design: Cohort (prospective)

Funding: Self-funded or unfunded

Setting: Population-based


David C. Slawson, MD
Professor and Vice Chair of Family Medicine for Education and Scholarship
Atrium Health
Professor of Family Medicine, UNC Chapel Hill
Charlotte, NC

Discuss this POEM



Impact assessment


Jonathan Tejada

Practice changing

practice changing


OTC Melatonin supplements

Poor quality control in production. Caveat emptor.