Vitamin D supplementation slightly reduces diabetes diagnoses in at-risk adults

Clinical Question

In adults with prediabetes, can vitamin D supplementation decrease their likelihood of developing type 2 diabetes over several years?

Bottom line

Vitamin D supplementation, over a median of 3 years, slightly reduces the diagnoses of diabetes in older people at risk of developing type 2 diabetes (NNT = 18 - 115). The benefit is greater in patients who achieve higher serum levels of vitamin D. 1a

Study design: Systematic review

Funding: Self-funded or unfunded

Setting: Various (meta-analysis)

Reviewer

Allen F. Shaughnessy, PharmD, MMedEd
Professor of Family Medicine
Tufts University
Boston, MA


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Comments

Anonymous

Diabetes and Vit D supplementation

Small but useful effect

ARUP KUMAR DHARA

Impact assessment

Very good

Anonymous

Minimal advantage with Vitamin D

Certainly inconclusive data.

Cristina Fasie-Neagoe

N

I agree

Robert Wallace Shepherd

Vitamin D supplementation slightly reduces diabetes diagnose

It would be helpful to know what dose of vitamin D was used in the studies.