Withholding platelet transfusion from thrombocytopenic patients with central venous catheters = more bleeding events

Clinical Question

Should patients with thrombocytopenia receive a platelet transfusion prior to ultrasound-guided central venous catheter placement?

Bottom line

Withholding a prophylactic transfusion of platelets from patients with thrombocytopenia who require CVC placement results in more catheter-related bleeding events. 1b

Study design: Randomized controlled trial (nonblinded)

Funding: Foundation

Setting: Inpatient (any location)


Nita Shrikant Kulkarni, MD
Assistant Professor in Hospital Medicine
Northwestern University
Chicago, IL

Discuss this POEM