Enterosgel effective for irritable bowel syndrome with diarrhea (NNT = 8)

Clinical Question

Is enterosgel safe and effective for the treatment of diarrhea-predominant irritable bowel syndrome?

Bottom line

Enterosgel appears to safely provide a moderate symptomatic benefit for persons with IBS-D. Its cost is $65 for a 3-pack of 225-g tubes on Amazon.com, which is approximately 11 days' worth at the most common study dose of 30 g twice daily. We don't know if it is better than other simple measures like fiber supplementation. 1b

Study design: Randomized controlled trial (double-blinded)

Funding: Industry

Setting: Outpatient (any)

Reviewer

Mark H. Ebell, MD, MS
Professor
University of Georgia
Athens, GA


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Comments

ARUP KUMAR DHARA

Impact assessment

Excellent

Anonymous

Enerosgel

See above

Anonymous

IBS dia

Very expensive