Improved outcomes with complete revascularization in older adults with myocardial infarction (FIRE)

Clinical Question

In older patients with myocardial infarction, does complete revascularization lead to better clinical outcomes than intervention of the culprit lesion only?

Bottom line

Patients 75 years or older with either ST-elevation or non-ST elevation MI have improved clinically important outcomes with complete, rather than culprit lesion-only, revascularization. This finding is similar to the findings in younger patients. 1b-

Study design: Randomized controlled trial (nonblinded)

Funding: Industry + foundation

Setting: Inpatient (any location) with outpatient follow-up

Reviewer

Nita Shrikant Kulkarni, MD
Assistant Professor in Hospital Medicine
Northwestern University
Chicago, IL


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Comments

ARUP KUMAR DHARA

Impact assessment

Excellent

Anonymous

Not enough information

I a curious as to what tests were done to determine ‘physiologic’ significance

Anonymous

INPROVED OUTCOME WITH COMPLETE REVASCULARIZATIONIN OLDER AD

GOOD TO KNOW