Mediterranean and low-fat diets minimally decrease mortality in patients at high risk of cardiovascular disease

Clinical Question

In patients at high risk of cardiovascular disease, what is the effect of specific diets on mortality and cardiovascular events?

Bottom line

This meta-analysis, which did not include low-carbohydrate/high-fat diets or intermittent fasting (for lack of research), found the Mediterranean diet (increased fish, fruit, and vegetable intake and A LOT of olive oil) and low-fat dieting to be associated with a small benefit on reducing mortality and cardiovascular disease in patients with at least 2 risk factors. The small net benefit makes me wonder whether we should devote so much time to asking about and trying to affect diet, even in patients at high risk of adverse cardiovascular outcomes. 1a-

Study design: Meta-analysis (randomized controlled trials)

Funding: Self-funded or unfunded

Setting: Various (meta-analysis)

Reviewer

Allen F. Shaughnessy, PharmD, MMedEd
Professor of Family Medicine
Tufts University
Boston, MA


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Comments

Anonymous

Diet and CV Risk

The American College of Lifestyle Medicine has good evidence on how lifestyle, including diet, can reduce CV risk

Arup Kumar Dhara

Impact assessment

Excellent

Anonymous

Diet and CV disease

The best diet is the one that keeps one's weight in the normal BMI range.

John W. Alvarez de Lorenzana

Seriously?

To see the reviewer say “The small net benefit makes me wonder whether we should devote so much time to asking about and trying to affect diet” really sums up how ignorant we still are in medicine today. When it comes to health and diet it’s sad to see this attitude permeating our CPD

Anonymous

MEDITERIEN AND LOW FAT DIET

GOOD TO KNOW

Anonymous

diète méditerranéenne

le problème avec ce genre d'étude, c'est comment il font pour mesurer la réelle adhérence des patients à la diète en question

Anonymous

dietary interventions

May enhance medications on health