Intranasal zavegepant is moderately superior to placebo for acute migraine in adults

Clinical Question

Is intranasal zavegepant effective in relieving acute migraine attacks in adults?

Bottom line

In this large study, the newly approved intranasal zavegepant was moderately superior to placebo in helping adults with acute migraine become pain free within 2 hours of treatment. 1b

Study design: Randomized controlled trial (double-blinded)

Funding: Industry

Setting: Outpatient (specialty)

Reviewer

Henry C. Barry, MD, MS
Professor
Michigan State University
East Lansing, MI


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Comments

Anonymous

Savegepant - Migraine

Moderately superior - to placebo! And comparatively to intranasal triptans et al?

DR ARUP KUMAR DHARA

Impact assessment

Excellent

Anonymous

acute migraine relief

intranasal zavegepant