A daily multivitamin has modest impact on memory in older adults (COSMOS-WEB)

Clinical Question

Does a multivitamin prevent decline in cognitive function in older adults?

Bottom line

Your patients may hear from the Centrum Silver folks (who co-sponsored this study) about the benefits of multivitamins on cognition. This study shows there is a modest improvement in one measure of memory, with no improvement in other cognitive outcomes. 1b-

Study design: Randomized controlled trial (double-blinded)

Funding: Industry + govt

Setting: Population-based

Reviewer

Mark H. Ebell, MD, MS
Professor
University of Georgia
Athens, GA


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Comments

ARUP KUMAR DHARA

Impact assessment

Excellent

Anonymous

soft recommendations for multivitamins

As expected, soft findings regarding multivitamins. Would take a much bigger sample size and looking at a wide variety of disease states

Robert Wallace Shepherd

Daily multivitamin slightly improves memory in older adults

The vitamin manufacturer Centrum would not have submitted the study for publication if the investigation showed no improvement (a negative study). How can clinicians have access to negative studies?

Anonymous

multivitamins

good to know