Bivalent respiratory syncytial virus (RSV) vaccine given to mothers reduces total and severe RSV infections in infants

Clinical Question

Does maternal respiratory syncytial virus (RSV) vaccination safely reduce the likelihood of RSV in their newborns?

Bottom line

A bivalent RSV vaccine given to pregnant women between 24 and 36 weeks' gestation safely reduces the likelihood of severe RSV in their newborns (NNT = 81 at 6 months of age). 1b-

Study design: Randomized controlled trial (double-blinded)

Funding: Industry

Setting: Outpatient (any)

Reviewer

Mark H. Ebell, MD, MS
Professor
University of Georgia
Athens, GA


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Comments

Arup Kumar Dhara

Impact assessment

Excellent

Anonymous

RSV

HELPFUL