Early anticoagulation after ischemic stroke is a safe strategy (ELAN)

Clinical Question

How safe and effective is early initiation of anticoagulation in patients with atrial fibrillation and acute ischemic stroke?

Bottom line

Early initiation of anticoagulation with a DOAC following acute ischemic stroke in patients with atrial fibrillation does not lead to an increased risk of symptomatic intracranial hemorrhage and may be more effective in preventing recurrent stroke. 1b

Study design: Randomized controlled trial (nonblinded)

Funding: Government

Setting: Inpatient (any location) with outpatient follow-up

Reviewer

Nita Shrikant Kulkarni, MD
Assistant Professor in Hospital Medicine
Northwestern University
Chicago, IL


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Comments

ARUP KUMAR DHARA

Impact assessment

Excellent

Anonymous

EARLY ANTICOGULANT AND IN ISCHIMIC STROKE

GOOD TO KNOW