Time to lactogenesis stage II is noninferior with immediate vs delayed etonogestrel implant insertion

Clinical Question

Is time to lactogenesis stage II similar with an etonogestrel implant insertion immediately postpartum versus 24 to 48 hours later?

Bottom line

Onset of lactogenesis stage II by day 3 postpartum did not differ between groups that had an ETG implant placed within 2 hours after delivery versus at 24 to 48 hours postpartum. The mean time to lactogenesis stage II slightly favored the immediate implant group. 1b

Study design: Randomized controlled trial (nonblinded)

Funding: Self-funded or unfunded

Setting: Inpatient (any location)


Linda Speer, MD
Professor and Chair, Department of Family Medicine
University of Toledo
Toledo, OH

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Impact assessment

Very 6


Estrogen implant postpartum

Had no idea estrogen implants weed used postpartum to boost milk production and provide contraception


Postpartum Nexplanon use in women wishing to breastfeed

I liked this study in general, but they didn’t look at, or at least they didn’t report, one key outcome: the total number of women in each group that were able to successfully breastfeed their babies. The study only included women who wished to both breastfeed their babies and have birth control through Nexplanon so why not include the number of women in each group that were successful in breastfeeding?


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