Access to POEMs and Essential Evidence Plus will no longer be included in CMA membership as of Dec. 1, 2023.
Clinical Question
Can advice to wash hands frequently reduce the transmission of respiratory infections?
Bottom line
A brief online handwashing intervention reduced respiratory infections. 1b
Reference
Study design: Randomized controlled trial (nonblinded)
Funding:
Setting: Population-based
Synopsis
Research Brief #4 (Little, 2015) A UK trial randomized 20,066 persons living in households with others to receive either access to a brief online handwashing intervention or no access. The primary outcome - the likelihood that a participant had a respiratory tract infection during a 4-month period - was decreased in the intervention group (51% vs 59%; P < .001; number needed to treat [NNT] = 12). The intervention also decreased the number of gastrointestinal infections (21% vs 25%; P < .001; NNT = 25) and the number of respiratory infections in a household member (44% vs 49%;P < .001; NNT = 20). The intervention has been updated for COVID-19 and is freely available at germdefence.org.
Reviewer
Mark H. Ebell, MD, MS
Professor
University of Georgia
Athens, GA
Comments
Significance
Are these numbers statistically significant ?