Login

POEMs by Essential Evidence Plus

Looking to stay current?

POEMs are synopses of new evidence, carefully filtered for relevance to patient care and evaluated for validity by the Essential Evidence Plus editorial team.

To get started, browse by year of publication below. For specific topics and a fully searchable POEMs archive, use Essential Evidence Plus.

Exclusive to CMA members
Sign up for daily POEMs emails
POEMs
Clinical Relevance of Information Index
!
December  
31 Increased water intake decreases UTI recurrence in women 72 % (n=1899)
28 Aspirin's benefits and harms are less clear for primary prevention in moderate-risk patients (ARRIVE) 68 % (n=1769)
27 Short-term outcomes for new-onset mild carpal tunnel syndrome better with steroid injection than splints 57 % (n=1674)
24 Adding CCTA to chest pain assessment reduces likelihood of nonfatal MI (SCOT-HEART) 35 % (n=1503)
21 Limited data: deprescribing is safe, but at the risk of symptom recurrence 63 % (n=1587)
20 Aspirin alone may be sufficient protection from postop VTE after total knee arthroplasty 40 % (n=1518)
19 Transcranial magnetic stimulation = sham TMS for motor recovery after stroke (NICHE) 20 % (n=1496)
18 Hospital at home provides equivalent results at lower cost for mild COPD exacerbations 47 % (n=1473)
17 Failure to wear a helmet while motorcycling is bad for your head 53 % (n=1756)
14 Subacute cough treatments: limited data, unclear benefits 67 % (n=1749)
13 No reduction in delirium with the use of haloperidol or ziprasidone in critically ill patients 25 % (n=1529)
12 Select adult patients can be safely discharged directly home from an ICU 21 % (n=1356)
11 USPSTF 2018 recommends intimate partner violence screening in women of reproductive age (B recommendation) 52 % (n=1343)
10 ATS guideline for managing patients with malignant pleural effusion 25 % (n=1391)
07 Low-dose theophylline is minimally helpful, if at all, in preventing COPD exacerbations 45 % (n=1484)
06 Clinical factors modestly accurate in predicting poor outcomes in older patients with dizziness (RODEO) 40 % (n=1306)
05 Amitriptyline ineffective for chronic back pain 63 % (n=1731)
04 Effective systemic treatments for pyoderma gangrenosum 18 % (n=1354)
03 Two bedside tests are fairly accurate in screening for delirium in older patients 40 % (n=1404)
November  
30 Lorcaserin is safe, but only modestly effective (6 pounds greater weight loss than placebo) 39 % (n=1468)
29 Extended rivaroxaban prophylaxis following a medical inpatient stay does not provide a net benefit (MARINER) 37 % (n=1513)
28 Increased mortality with piperacillin-tazobactam for ESBL bacteremia 31 % (n=1465)
27 Statins ineffective for primary prevention in patients 75 years or older without diabetes 68 % (n=1650)
26 CATCH2 score accurate to identify children with minor head injury who need CT 43 % (n=1507)
23 Gabapentin and pregabalin not effective for low back pain with or without radiculopathy 70 % (n=1792)
22 NSAID use near conception is associated with early miscarriage in women with BMI <25 52 % (n=1627)
21 Intravenous oxytocin better than intramuscular to prevent postpartum hemorrhage 23 % (n=1473)
20 60% of adults treated with abx for acute appendicitis do not require appendectomy at 5 years 40 % (n=1718)
19 Incidence and outcomes of sudden cardiac death in athletes 38 % (n=1650)
16 MRI-guided thrombolysis can reduce likelihood of disability in patients with stroke of unknown symptom onset (WAKE-UP) 26 % (n=1372)
15 Immediate reduction more effective than a gradual approach for smoking cessation 64 % (n=1619)
14 Shorter time to delivery with concurrent balloon cervical ripening and oxytocin in multiparas 18 % (n=1342)
13 Sometimes our word choices turn good news into bad news 77 % (n=1497)
12 Paracervical block reduces pain with IUD placement 32 % (n=1500)
09 Rifampin for 4 months preferred to isoniazid for 9 months for latent TB in high-risk patients 30 % (n=1523)
08 Acupuncture effective for chronic prostatitis/chronic pelvic pain syndrome 34 % (n=1579)
07 Shorter duration of antibiotics, similar success rates with algorithm-based therapy for staphylococcal bacteremia 32 % (n=1452)
06 Guideline, with no evidence, suggests annual screening for urinary incontinence in women 42 % (n=1574)
05 A single blood pressure measurement is often falsely elevated 77 % (n=1912)
02 Induction of labor at 39 weeks' decreases cesareans without increase in perinatal morbidity 25 % (n=1587)
01 Early endovenous ablation improves outcomes in patients with venous leg ulcers 35 % (n=1373)
October  
31 Screening for AAA in women not very effective 48 % (n=1583)
30 Aspirin + high-dose PPI prevents death and progression in patients with Barrett's esophagus (AspECT) 43 % (n=1623)
29 Providing procalcitonin levels does not reduce antibiotic use in patients with lower respiratory tract infections 28 % (n=1430)
26 Effectiveness of aspirin in primary prevention appears to vary by patient weight 52 % (n=1650)
25 Patient-reported noninfectious complications common after urethral catheter placement 47 % (n=1539)
24 Noninvasive vagus nerve stimulation more effective than sham therapy for migraine attacks (PRESTO) 32 % (n=1457)
23 Guidelines for treating reflux in infants and children 52 % (n=1648)
22 NSAIDs harmful in treating women with uncomplicated UTI 61 % (n=1859)
19 Tamsulosin not effective to hasten smaller ureteral stone passage 50 % (n=1560)
18 Oral prednisolone = placebo in children with otitis media with effusion (OSTRICH) 50 % (n=1610)
17 Chronic sinusitis: saline irrigation helps somewhat; steroid doesn't add more benefit 57 % (n=1750)
16 USPSTF 2018: HPV testing alone every 5 years is acceptable screening in women 30 to 65 years old (A recommendation) 58 % (n=1641)
15 Fewer recurrences of patella dislocation in kids after surgery than after bracing 26 % (n=1523)
12 Aldosterone antagonists may be of benefit post-STEMI 31 % (n=1480)
11 Escitalopram reduces risk of adverse cardiac events in adults with depression and acute coronary syndrome 54 % (n=1693)
10 QOL of patients with multimorbidity is not improved with patient-centered care model 46 % (n=1523)
09 Proposed changes to diagnosis criteria labels millions more as hypertensive 60 % (n=1469)
08 USPSTF 2018: insufficient evidence to recommend screening for AFib with ECG (I statement) 62 % (n=1683)
05 Low-quality evidence: probiotics = placebo in preventing infections in the elderly 49 % (n=1594)
04 Decompression surgery no more effective than exercise for shoulder impingement syndrome 51 % (n=1652)
03 Isoniazid-rifapentine regimen for latent TB infection is safe and effective 26 % (n=1463)
02 Lower systolic BP during antihypertensive treatment associated with more deaths in the elderly 66 % (n=1762)
01 Point-of-care BNP testing may be helpful to rule out heart failure 42 % (n=1513)
September  
28 Women with ER+/HER-/node- breast cancer and intermediate Oncotype score do not benefit from chemo (TAILORx) 25 % (n=1370)
27 Advance care planning increases execution of advance directives and surrogate decision-maker assignment 57 % (n=1484)
26 Physical activity associated with reduced incidence of depression 73 % (n=1768)
25 USPSTF 2018: insufficient evidence to recommend PAD screening (I statement) 54 % (n=1549)
24 Dupilumab modestly reduces asthma exacerbations at a high price 28 % (n=1437)
21 Endovascular denervation lowers blood pressure (RADIANCE-HTN SOLO) 23 % (n=1377)
20 Ratio of AFP in vaginal blood to maternal serum is a marker for pregnancy failure 27 % (n=1421)
19 USPSTF 2018: insufficient evidence to recommend nontraditional risk factors for CVD screening (I statement) 56 % (n=1483)
18 Gabapentin ineffective for vulvodynia 32 % (n=1574)
17 NOACs preferred over warfarin for nonvalvular atrial fibrillation in patients also taking low-dose aspirin 59 % (n=1652)
14 Acupuncture may reduce aromatase inhibitor–related arthralgia in women with breast cancer 27 % (n=1437)
13 Arthroscopy better than personalized physical therapy in young people with femoroacetabular impingement syndrome 27 % (n=1525)
12 No benefit with restrictive fluid strategy during perioperative period for major abdominal surgery 26 % (n=1522)
11 Clopidogrel + aspirin provides more net benefit than aspirin alone after minor stroke or TIA 54 % (n=1687)
10 Digital media use associated with ADHD symptom development among adolescents 48 % (n=1597)
07 Children with first complex febrile seizure are at low risk for subsequent seizure in hospital 31 % (n=1574)
06 Attempted external cephalic version not associated with perinatal morbidity 20 % (n=1452)
05 LABA + ICS reduces exacerbations (NNT = 53 over 6 months), but not hospitalizations 62 % (n=1529)
04 Human albumin infusions improve mortality in patients with persistent ascites (ANSWER) 26 % (n=1377)
03 Less renal replacement therapy with sodium bicarbonate infusion for patients with severe metabolic acidosis 20 % (n=1308)
August  
31 USPSTF 2018 recommends screening to prevent osteoporotic fractures in women 65 years and older (B recommendation) 65 % (n=1612)
30 Standard of practice that encourages oral and subcutaneous opioids leads to decreased IV opioids 36 % (n=1484)
29 No reduction in medical errors with increased direct supervision of resident teams 29 % (n=1429)
28 Persistence improves HPV vaccine uptake 57 % (n=1601)
27 USPSTF 2018 recommends counseling 55 to 69-year-old men on benefits and harms of prostate cancer screening (C recommendation) 66 % (n=1622)
24 Incidental findings are common with chest CT and MRI of the spine and brain 64 % (n=1616)
23 Poor-quality data show music interventions may improve post-op anxiety and pain in adults 20 % (n=1457)
22 Stress-related disorder increases risk of subsequent autoimmune disease 46 % (n=1660)
21 Good reasons not to lower the definition of high blood pressure in adults 70 % (n=1779)
20 Fremanezumab effective for episodic migraine 34 % (n=1429)
17 Extracorporeal membrane oxygenation probably does not significantly reduce mortality in severe ARDS 11 % (n=1340)
16 Stigmatizing language in chart notes creates negative impressions 63 % (n=1740)
15 Vitamin D reduces risk of parent-reported wheezing in first year among preterm black infants 23 % (n=1523)
14 Lower risk of atrial fibrillation with addition of vasopressin to catecholamines for treatment of shock 18 % (n=1415)
13 NPH insulin: fewer episodes of severe hypoglycemia than analogs (Lantus and Levemir) and less than half the cost 64 % (n=1689)
10 Oral contraceptives and anti-androgens most effective for hirsutism pharmacotherapy 49 % (n=1680)
09 USPSTF 2018 recommends against screening resting/exercise ECG for asymptomatic adults at low risk of CVD (D recommendation) 63 % (n=1679)
08 Additional evidence of no increased survival benefit to intensive follow-up after colorectal cancer surgery 42 % (n=1671)
07 Mifepristone pretreatment improves success rate of misoprostol for early pregnancy loss 31 % (n=1537)
06 Nonadvanced colon adenoma may not increase colorectal cancer risk 50 % (n=1639)
03 Adding cytology to HPV testing slightly improves cancer and precancer detection 52 % (n=1580)
02 Radial artery grafts reduce risk of revascularization compared with saphenous vein graft in CABG 21 % (n=1543)
01 Children of consanguineous parents are at increased risk of mood disorders and psychoses 21 % (n=1667)
July  
31 Maternal and neonatal risks and benefits associated with bariatric surgery 28 % (n=1582)
30 As-needed use of budesonide plus formeterol as good as daily use of steroid (SYGMA 2) 61 % (n=1555)
27 Acupuncture effective for chronic pain conditions 59 % (n=1738)
26 Fewer exacerbations but somewhat more pneumonia with triple inhaler therapy for COPD (IMPACT) 57 % (n=1529)
25 Estrogen no better than vaginal lubricant for postmenopausal vaginal symptoms 63 % (n=1876)
24 Habit reversal improves skin score by reducing scratching in children with atopic dermatitis 49 % (n=1568)
23 Vertebroplasty = sham procedure for compression fractures 35 % (n=1757)
20 Bath oil does not improve eczema symptoms in children (BATHE) 52 % (n=1722)
19 Steroid + SABA similar to daily steroid for preventing exacerbations in mild asthma (SYGMA) 63 % (n=1666)
18 Vareniciline, bupropion may not increase risk of cardiovascular events 53 % (n=1695)
17 Breast cancer screening with MRI: more false-positives, more biopsies 51 % (n=1771)
16 Very few patients with syncope have pulmonary emboli 41 % (n=1748)
13 Second blood pressure reading drops 8 mm Hg from initial high reading 76 % (n=1945)
12 Restrictive transfusion strategy increases cardiac events in patients undergoing orthopedic surgery 25 % (n=1569)
11 Acupuncture, CBT, stress reduction, yoga offer a small benefit for chronic back pain 60 % (n=1696)
10 Relaxed hemoglobin A1c goals for T2DM from the American College of Physicians 69 % (n=1825)
09 Continuous glucose monitors reduce hypoglycemia in adults with type 1 DM and hypoglycemia unawareness (HypoDE) 42 % (n=1603)
06 Procalcitonin reduces antibiotic prescribing for acute bronchitis but not other causes of lower respiratory tract infection 30 % (n=1503)
05 Vitamin E = placebo for relief of neuropathic symptoms in patients with diabetes (VENUS) 40 % (n=1686)
03 Guidewire exchange of PICCs associated with higher risk of thrombosis 21 % (n=1478)
02 No benefit to supplemental oxygen in patients with acute MI and normal oxygen saturation 43 % (n=1736)
June  
29 Risk of cancer is low in patients with Barrett's esophagus 48 % (n=1768)
28 Home-based exercise with coach and wearable activity monitor (eg, Fitbit) no better than usual care for PAD 41 % (n=1637)
27 Cannabinoids somewhat helpful for nausea, maybe helpful for spasticity, probably not helpful for non-neuropathic pain 50 % (n=1791)
26 Optimal regimen of aspirin to prevent preeclampsia may also prevent placental abruption or antepartum hemorrhage 27 % (n=1566)
25 Ambulatory blood pressure important for decision-making about treatment 71 % (n=1823)
22 Mixed results from studies of steroids for septic shock (APROCCHSS, ADRENAL) 21 % (n=1455)
21 For carefully selected stroke patients, endovascular thrombectomy is beneficial at 6 to 16 hours after onset (DEFUSE) 30 % (n=1486)
20 American Academy of Pediatrics guidelines for treating depression in adolescents 59 % (n=1637)
19 Febuxostat increases all-cause and CV mortality compared with allopurinol 56 % (n=1694)
18 Improved kidney outcomes with intravenous balanced crystalloids instead of saline 35 % (n=1622)
15 High-flow oxygen helpful in hospitalized infants with bronchiolitis 24 % (n=1455)
14 Five-day nitrofurantoin superior to single-dose fosfomycin for women with uncomplicated UTI 71 % (n=1879)
13 Risk of subsequent advanced adenoma or CRC in patients with low-risk adenoma on baseline colonoscopy 48 % (n=1582)
12 Society of Hospital Medicine recommendations for safe opioid use for hospitalized patients 43 % (n=1503)
11 Nothing works for cough associated with the common cold 72 % (n=1919)
08 Liberal oxygen therapy in hospitalized patients: too much of a good thing? (IOTA) 38 % (n=1658)
07 Biannual azithromycin reduces all-cause mortality in preschool children in sub-Saharan Africa 7 % (n=1371)
06 The progression rate is low for cervical intraepithelial neoplasia grade 2 45 % (n=1542)
05 Catheter ablation reduces mortality for patients with heart failure and atrial fibrillation (CASTLE-AF) 37 % (n=1626)
04 Antidepressants, watchful waiting poorly studied in primary care patients with mild-moderate depression 61 % (n=1751)
01 Budesonide inhaler ineffective for same-day prevention of acute mountain sickness 22 % (n=1629)
May  
31 Bright light therapy at midday beneficial for patients with bipolar depression 41 % (n=1422)
30 Urinalysis effective to exclude UTI in febrile infants younger than 60 days 45 % (n=1684)
29 Women with normal Pap smears in their 50s unlikely to develop cervical cancer as they age 63 % (n=1876)
28 Outcomes better with CABG than PCI in patients with diabetes or multivessel disease 40 % (n=1661)
25 Osteoporosis screening in older women: fewer hip fractures but no overall reduction in fractures 56 % (n=1677)
24 Systolic blood pressure at least 140 mm Hg best place to begin treatment 71 % (n=1786)
23 MA: Low-quality evidence finds DRE screening for prostate cancer inaccurate 60 % (n=1715)
22 In low-risk patients with ACS, noninvasive testing adds little to clinical evaluation 44 % (n=1663)
21 Corticosteroids improve outcomes in patients with severe community-acquired pneumonia 44 % (n=1733)
18 USPSTF 2018 recommends counseling about minimizing exposure to UV radiation to prevent skin cancer (B recommendation) 64 % (n=1664)
17 Intensive primary care weight-loss program results in remission for half of patients with T2DM (DiRECT) 63 % (n=1727)
16 Antenatal magnesium sulphate is neuroprotective for infants born preterm 24 % (n=1622)
15 Nonopioids equivalent to opioids for severe chronic back, hip, or knee pain with fewer adverse outcomes 74 % (n=1888)
14 MA: Ultrasound accurately diagnoses small bowel obstruction 36 % (n=1743)
11 HPV testing better than cytology for women vaccinated against HPV 49 % (n=1552)
10 Low-intensity PSA-based screening does not reduce mortality, but leads to overdiagnosis and potential harm 62 % (n=1695)
09 Self-monitoring BP leads to lower blood pressure compared with office monitoring 61 % (n=1812)
08 Increased vaccine exposure not linked to increased risk of non-vaccine-targeted infections in children 60 % (n=1743)
07 Fewer recurrences of small umbilical hernias repaired with mesh than with sutures 32 % (n=1716)
04 Long-acting muscarinic antagonists + inhaled steroids = long-acting B-agonists + inhaled steroids 61 % (n=1554)
03 Triple antiplatelet tx increases bleeding and no better than standard therapy for preventing TIA and recurrent CVA (TARDIS) 49 % (n=1740)
02 Nonbenzodiazepine hypnotic drugs are associated with increased fractures in older adults 67 % (n=1879)
01 Single maintenance and reliever therapy more effective than inhaled steroids and short-acting B-agonists for asthma (SMART) 63 % (n=1664)
April  
30 PCI = sham PCI for exercise tolerance in patients with stable angina plus severe CAD (ORBITA) 40 % (n=1679)
27 Medications ineffective to prevent cognitive decline or dementia 61 % (n=1762)
26 AAN guideline for patients with mild cognitive impairment 60 % (n=1736)
25 Calcium and vitamin D, alone or combined, do not reduce fracture risk in community-dwelling older adults 62 % (n=1852)
24 Remission or recovery common after a first episode of psychosis 40 % (n=1728)
23 Adults with varicose veins are at increased risk of DVT 52 % (n=1845)
20 Denying some patient requests worsens patient satisfaction with their care 61 % (n=1816)
19 Aspirin no different than rivaroxaban for prevention of VTE after TKA or THA 48 % (n=1898)
18 USPSTF 2018 recommends against screening for ovarian cancer in asymptomatic women (D recommendation) 61 % (n=1808)
17 Fewer recurrent strokes with PFO closure than medical treatment in patients with cryptogenic stroke 21 % (n=1567)
16 Prophylactic haloperidol does not improve survival or prevent delirium in critically ill patients 28 % (n=1745)
13 Vaginal progesterone does not lessen preterm birth for high-risk women 23 % (n=1647)
12 Hydrolyzed infant formula does not reduce the risk of type 1 diabetes 29 % (n=1594)
11 Postexposure prophylaxis with doxycycline reduces STIs in men having sex with men 33 % (n=1687)
10 Edoxaban as effective as LMWH for treatment of cancer-associated VTE 35 % (n=1655)
09 Avoiding cow's milk does not reduce celiac disease in high-risk infants 31 % (n=1706)
06 Surgery = no surgery for patients with subacromial shoulder pain (CSAW) 49 % (n=1736)
05 Pulmonary embolism rule-out criteria reduces the need for CT pulmonary angiography in low-risk patients (PERC) 45 % (n=1720)
04 Tibetan yoga modestly improves fatigue and sleep quality in women with breast cancer undergoing chemotherapy 23 % (n=1561)
03 Transdermal estrogen and oral progesterone prevent depression in peri/postmenopausal women 54 % (n=1715)
March  
29 More MRI findings increase the likelihood of recent or recurrent back pain 50 % (n=1724)
28 SR: Short courses of antibiotics as effective as longer courses for outpatient infections 74 % (n=1911)
27 USPSTF 2018: evidence insufficient to recommend for or against idiopathic scoliosis screening (I recommendation) 44 % (n=1645)
26 Lung cancer screening may increase the likelihood of smoking cessation 53 % (n=1781)
23 Delay of more than 24 hours to hip fracture surgery associated with increased mortality 43 % (n=1747)
22 Statins effective for LDL 190 mg/dL or higher, regardless of risk level 61 % (n=1677)
21 Higher resource use and lower mortality associated with care by PCPs compared with hospitalists 36 % (n=1654)
20 Extensive intervention by hospital pharmacists led to decreased readmissions 43 % (n=1666)
19 Pain control similar, patient satisfaction slightly higher with patient-controlled analgesia in the ED 24 % (n=1587)
16 Stroke patients with imaging evidence of salvageable brain tissue benefit from late thrombectomy 35 % (n=1617)
15 Modern hormonal contraception associated with increased risk of breast cancer 62 % (n=1791)
14 Nonpharmacological interventions reduce labor pain and shorten labor 27 % (n=1636)
13 MRI using defined protocol is safe even in patients with older implanted cardiac devices 37 % (n=1568)
12 Drugs for chronic idiopathic constipation are similarly effective 62 % (n=1671)
09 Low prevalence of pulmonary embolism in patients who present to ED with syncope 42 % (n=1444)
08 Determining what matters to patients with multiple chronic diseases 60 % (n=1651)
07 "Surprise question" is moderately accurate for predicting likelihood of death 43 % (n=1694)
06 Patients experience shame and isolation for deciding not to pursue thyroid cancer treatment 38 % (n=1610)
05 Low rate of bacteremia in children hospitalized with pneumonia 30 % (n=1573)
02 Low-dose aspirin not useful for venous ulcers 42 % (n=1709)
01 FIT more acceptable with better detection rate than gFOBT for colorectal cancer screening 70 % (n=1816)
February  
28 Clinical diagnosis of Lyme disease frequently misses the "bull's-eye" 42 % (n=1608)
27 Cervical pessary prevented preterm birth among pregnant women with short cervix 18 % (n=1562)
26 Color Doppler is modestly accurate compared with biopsy in patients with suspected giant cell arteritis 28 % (n=1563)
24 Italian lung cancer screening findings consistent with US National Lung Screening Trial results (ITALUNG) 61 % (n=64)
23 Lumbar fusion of variable value based on treating diagnosis, with significant complication rates 45 % (n=1627)
22 No benefit with use of periprocedural sodium bicarbonate or acetylcysteine in patients with CKD and angiography 25 % (n=1485)
21 Continuous glucose monitoring improves outcomes in pregnant women with type 1 diabetes (CONCEPTT) 23 % (n=1516)
20 Early hydrocortisone ineffective in improving outcomes in patients with septic shock 22 % (n=1474)
16 PCI of culprit lesion alone compared with multivessel PCI results in fewer deaths in AMI with cardiogenic shock 26 % (n=1548)
15 CRC screening recommendations for average-risk and high-risk persons from US GI societies 58 % (n=1574)
14 Antenatal magnesium improves neurologic outcomes in infants 22 % (n=1653)
13 Fewer overall hospital days with use of indwelling pleural catheters vs pleurodesis for malignant effusions 20 % (n=1569)
12 No benefit with transfusion of fresh red cells compared with older red cells in critically ill patients 22 % (n=1615)
09 Injectable extended-release naltrexone effective for opioid dependence 33 % (n=1663)
08 Broad-spectrum abx increase adverse events in children with acute respiratory infections with minimal benefit 65 % (n=1795)
07 ACC/AHA guidelines take more aggressive, less evidence-based approach to hypertension management 67 % (n=1674)
06 MA: ultrasound is reasonably accurate in detecting synovitis in patients with rheumatoid arthritis 33 % (n=1671)
05 Early PT for acute low back pain is cost-effective, but gain in quality of life is likely too small to notice 62 % (n=1742)
02 Patients without AMI who take evolocumab have lower cholesterol levels 27 % (n=1451)
01 SR: poor quality evidence on outcomes of lactate point-of-care testing in patients with suspected sepsis 24 % (n=1487)
January  
31 Mepolizumab reduces need for surgery in adults with severe nasal polyposis 25 % (n=1483)
30 Immunonutrition does not decrease complications after abdominal surgery 16 % (n=1526)
29 Clicky hips don't necessarily mean dysplasia in infants 50 % (n=1796)
26 Oral capsule– and colonoscopy-delivered fecal transplant equally effective for recurrent C. difficile infection 30 % (n=1803)
25 Prediction tool for chronic kidney disease following acute kidney injury 33 % (n=1543)
24 Single question is useful for identifying acute mountain sickness in travelers at high altitude 15 % (n=1643)
23 Dual therapy with dabigatran and clopidogrel preferred after PCI for patients with AF (RE-DUAL PCI) 40 % (n=1647)
22 Exercise alone and various combinations of interventions reduces the risk of injurious falls in older adults 65 % (n=1821)
19 Ibuprofen + acetaminophen equals opioid + acetaminophen for acute severe extremity pain 71 % (n=1939)
18 Mepolizumab provides a small reduction in the exacerbations of moderate to severe eosinophilic COPD 24 % (n=1474)
17 Aqueous chlorhexidine similar to alcohol-based chlorhexidine for skin decontamination before minor skin surgery 48 % (n=1788)
16 Cardiac troponin often falsely elevated in patients at low risk 50 % (n=1880)
15 Ibuprofen and morphine provide similar post-op pain relief in kids; ibuprofen has fewer harms 47 % (n=1866)
12 Romosozumab prevents clinical fracture slightly better than alendronate in women with osteoporosis and previous fracture 39 % (n=1598)
11 Vitamin D replacement increases blood levels but doesn't affect fatigue 47 % (n=1908)
10 Additional testing of limited benefit in patients with new-onset chest pain 48 % (n=1713)
09 Minimal effect of ERT on sexual function in menopausal women 46 % (n=1677)
08 High-sensitivity troponin I of less than 5 ng/L has negative predictive value of 99.9% for cardiac death at 1 year 41 % (n=1628)
05 Reliability of some clinical exam findings is dubious in children with suspected pneumonia 55 % (n=1653)
04 Short-term use of vitamin D = placebo in children with autism 29 % (n=1694)
03 Rivaroxaban + aspirin somewhat better than aspirin alone for tertiary prevention of CVD (COMPASS) 48 % (n=1618)
02 One third of patients with anxiety disorder will relapse when SSRI/SNRI treatment stops 69 % (n=1752)
Exclusive to CMA members

Sign up for daily POEMs emails