RSV vaccine is safe and effective in adults 60 years and older, but the absolute risk reduction is small

Question clinique

How effective is a bivalent respiratory syncytial virus (RSV) vaccine at preventing RSV infection in adults 60 years and older?

L’Essentiel

The RSV vaccine is 67% effective, with an NNT of 472 to prevent any symptomatic infection. The investigators argue that this is still important at a population level because of prolonged shedding and potential transmission of RSV among older infected adults. 1b

Plan de l'etude: Randomized controlled trial (double-blinded)

Financement: Industry

Cadre: Population-based

Reviewer

Mark H. Ebell, MD, MS
Professor
University of Georgia
Athens, GA


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Commentaires

ARUP KUMAR DHARA

Impact assessment

Excellent