Question clinique
How long do symptoms persist in patients who were hospitalized with COVID-19?
L’Essentiel
This study provides further evidence of the long-term persistence of COVID-19 symptoms. Approximately 30% of patients hospitalized with COVID-19 infection will have persistent symptoms for at least 60 days. 2c
Référence
Plan de l'etude: Cohort (retrospective)
Financement:
Cadre: Population-based
Sommaire
Research Brief #75: Many patients with symptomatic COVID-19 infection have persistent symptoms after the acute illness. We previously summarized a study from France, in which 60% of 150 patients with mild to moderate COVID-19 infection had persistent symptoms 30 days after illness onset, and 30% had persistent symptoms 60 days after onset of the illness. The symptoms were mainly fatigue, shortness of breath and loss of taste and smell (https://www.essentialevidenceplus.com/content/poem/221121) This larger observational study gives the outcomes of 1,648 patients with COVID-19 discharge from 38 Michigan hospitals between 16 March and 1 July 2020. Within 60 days of discharge, of the 1,250 (76%) patients who survived hospitalization, an additional 84 died and 189 patients were re-hospitalized. Of the patients alive 60 days after discharge, 488 (42%) were successfully contacted and completed a post-discharge telephone survey. Cardiopulmonary symptoms (such as cough and dyspnea) were reported by 159 (33%) patients, and 65 (13%) patients had persistent loss of taste or smell. This study from Michigan hospitals confirms that roughly 30% of patients hospitalized with COVID-19 infection will have persistent symptoms for at least 2 months. A limitation of this study is that less than 50% of discharge patients were included in the study, which could lead to over- or under-estimation of the frequency of persistent symptoms
Reviewer
John Hickner, MD, MS
Professor Emeritus
Dept of Family Medicine
Michigan State University
East Lansing, MI
Commentaires
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